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First, SELECT was designed as a CV outcomes trial and not a weight-loss trial, and weight loss was only a supportive secondary endpoint in the trial design

Because it works upstream, your body's natural feedback systems stay active

We recently demonstrated increased CD38 expression in skin biopsies from patients with SSc, and correlation with clinical disease severity 24

Enhanced Energy Expenditure via NNMT Inhibition : In preclinical models, 5-Amino-1MQ increased whole-body metabolic rate by redirecting cellular resources away from fat storage and toward active ATP production