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A study based on Nrf2-KO (knockout of Nrf2) diabetic mice showed that syringaresinol inhibits pyroptosis caused by NLRP3/Caspase-1 in DN by activating the Nrf2/HO-1 signaling pathway [72]

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J Biochem 88(6):18951898 Kll L, Krogh A, Sonnhammer EL (2007) Advantages of combined transmembrane topology and signal peptide predictionthe Phobius web server

It was found that total antioxidant status and cell viability were higher in the group that N

doi: 10.3389/fpls.2025.1713590 Received 26 September 2025 Revised 13 October 2025 Accepted 11 November 2025 Published 08 December 2025 Volume 16 - 2025 Edited by Dr