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To determine whether increases in intracellular GSH directly enhance expression of T2-signature proteins in HAECs, we lowered intracellular GSH levels by inhibiting SLC7A11 using the chemical inhibitor erastin (16)

The ROC curve was 0.831 (95%CI 0.771-0.891), when compared to the NIHSS-8, RACE, and FAST-ED scales none was superior, and the CPSS scale was inferior (p = 0.011)

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As model of intestinal cancer-related cachexia, Apc Min/+ mice carry a nonsense point mutation in the Apc gene, leading to multiple intestinal polyps and tumors development