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The ability to shuttle between the +1, +2, and +3 oxidation states is responsible for the versatile chemistry of vitamin B 12 , allowing it to serve as a donor of deoxyadenosyl radical (radical alkyl source) and as a methyl cation equivalent (electrophilic alkyl source)

The MHRA advises periodic monitoring of B12 levels in at-risk or symptomatic patients taking metformin

Thiamine metabolism disorders and epilepsy The SLC19A3 gene is situated at 2q36.3 and encodes thiamine transporter protein 2 (THTR2)

Immune Function : Some B vitamins, including B6, B9, and B12, play roles in supporting immune function