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222 Notably, succinate levels increase in Bmal1-knockout macrophages

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Uses Substances From Your Body: The bodys own biological material is the foundation of PRP injections, minimizing the risk of allergic reactions or rejection that can occur with foreign substances

Simultaneously, melanocytes express co-stimulatory molecules (e.g., CD40, CD80) and adhesion molecules (e.g., ICAM-1), enabling them to present self-antigens to T cells, thereby promoting T cell proliferation and activation, ultimately contributing to vitiligo progression

doi: 10.1212/CON.0000000000000715 [PubMed] 31766004 Minicucci F, Ferlisi M, Brigo F, Mecarelli O, Meletti S, Aguglia U, Michelucci R, Mastrangelo M, Specchio N, Sartori S, Tinuper P