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This raises an intriguing question of whether alternative sources of energy, such as ketone bodies by-passing the glycolytic pathway, might lead to increases in energy, and indeed some studies showed a reduction in fatigue in ME/CFS on a ketone diet [80]

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While G6PD deficiency induced hemolytic anemia can cause hypoxia due to nonfunctioning, hemolyzed erythrocytes, it is important to also monitor the patient for methemoglobinemia