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Combined, these mechanisms help reduce extended inflammatory damage

Simultaneously, for fibromyalgia, a condition which shares many symptomatic parallels with ME/CFS, rectal insufflation ozone therapy has shown significant therapeutic potential [66]

The association between serum ferritin and colorectal cancer

Additionally, viral infections such as Epstein-Barr virus activating IDO may convert tryptophan to kynurenine, supporting this hypothesis [63,64,65,66]

The active form of vitamin D is capable of crossing the bloodbrain barrier, suggesting that vitamin D may have a direct or indirect role in brain and cognitive functions, as reported by Akpinar and Karadag (2022) [28]