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SKU: 18353899199 · From psychiatrist-in-kuwait.com

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Description

Accumulating findings further suggest that intestinal inflammation may trigger misfolding of -synuclein within enteric neurons, enabling its propagation to the brainstem via vagal pathways and providing a mechanistic link between gut pathology and dopaminergic neurodegeneration

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[PubMed: 4403626] 392

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Subsequently, IRF3 is phosphorylated by TBK1 in the complex, which promotes IRF3 homodimerization and translocation to the nucleus to further regulate the expression of a series of genes

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