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The detection of oxidative stress in patients can provide valuable insights into their disease status and help guide patient management strategies

Bimekizumab efficacy and safety in moderate to severe plaque psoriasis (BE READY): a multicentre, double-blind, placebo-controlled, randomised withdrawal phase 3 trial

These receptors can also assemble inflammasome complexes, such as NLR family pyrin domain containing 3 (NLRP3), in coordination with absent in melanoma 2 (AIM2), resulting in the release of pro-inflammatory cytokinesincluding interleukin-1 (IL-1), IL-18, and TNF-and thereby amplifying neuroinflammation (Harms et al., 2021

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& Brennum, J