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Although inflammation can be a protective response, sustained activation of neuroinflammatory pathways leads to neuronal injury and causes the progression of neurodegenerative disorders ( 2.5 Impaired protein degradation systems Dysfunction in systems responsible for protein degradation, such as the ubiquitin-proteasome system (UPS) and autophagy, contributes to the development of AD and PD

[DOI] [PMC free article] [PubMed] [Google Scholar] 79.Wu S.-S., Li Q.-C., Yin C.-Q., Xue W., Song C.-Q

And if you do you should take a look at the symptoms of Vitamin B12 deficiency so you know if supplementing is a good idea or not

However, some parents of children with CAH, as well as several patients with CAH, do not agree with this rigorous recommendation

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