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In order to gain insights into biological pathways associated with increasing emphysema severity within a patient and explore computational strategies for identifying COPD therapeutics, we obtained paired samples from eight regions at regular intervals between the apex and base of each explanted lung from six patients with severe COPD (Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage IV) and two donor lungs

In our study, however we did not observe differences between the two groups

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Diarrhea may occur as a side effect but should stop when your course is complete

Where indicated, HFF-1-containing media were also incubated with a different treatment of either 10 or 30 mM GSH, or 4 g/mL amikacin alone, or a combination of 10 mM GSH + 4 g/mL amikacin, either in the presence or absence of bacteria