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36 As 85% of aconitase in the brain is the mitochondrial isozyme, a decrease in brain aconitase activity is considered a sensitive indicator of excess mitochondrial superoxide production

Several signal transduction pathways involved in fungal differentiation also play key roles in cancer progression, highlighting the commonality between them

67 GrubbsC

Under physiological conditions, these ROS act as secondary messengers involved in redox signaling, modulating processes such as differentiation, matrix turnover, and cellular adaptation to mechanical load (Sun et al., 2025)