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Glutathione-PEGylated liposomal methylprednisolone in comparison to free methylprednisolone: slow release characteristics and prolonged lymphocyte depression in a first-in-human study

10.1186/s12967-024-06019-4 84 LuJ.LiuZ.ShuM.ZhangL.XiaW.TangL.et al (2021)

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Signs of B12 Deficiency: Dizziness Pins and needles Pale complexion Forgetfulness Unexplained fatigue Vision issues Muscle weakness Smooth tongue Mood changes These symptoms may indicate a Vitamin B12 deficiency and should not be ignored

Post-synaptic glutamate receptors and MAGUKs, and pre-synaptic Bassoon, vGlut1, SYT1, and Synaptophysin appear to share a modular organization where the number but not size of puncta of these proteins increase with increases in spine size 25,41,42,44