2121-A USE OF NIS4 IN PRIMARY CARE AND ENDOCRINOLOGY CLINICS IDENTIFIES PEOPLE WITH TYPE 2 DIABETES AT A HIGHER RISK OF SEVERE NONALCOHOLIC STEATOHEPATITIS Srilaxmi Kalavalapalli 1 , Eddison GodinezLeiva 1 , Romina Lomonaco 1 , Stephen Marangi 1 , Enrique ValdezSaenz 1 , Andrea Ortiz Rocha 1 , Yasmine Mohseni 1 , Margery Connelly 1 , Toni Prezant 2 , Kelly Chun 2 , Maria Lupi 1 , Juan Munoz Pena , 1 , Juan Perdomo Rodriguez 1 , Jeffrey Budd 1 , Anu Sharma 1 , Diana Barb 1 and Kenneth Cusi 1 , (1)University of Florida, (2)Labcorp Background: The noninvasive diagnosis of nonalcoholic steatohepatitis (NASH) remains challenging
GCL gene expression is upregulated under conditions where Zn increased cellular defense response is necessary
Consequently, advancing these frontier strategies toward clinical application necessitates not only continuous technical optimization to reconcile intrinsic trade-offs but also urgent, parallel breakthroughs in standardized verification protocols and scalable, safety-controlled manufacturing processes
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