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Charache, S

Histological analyses of skin biopsies taken from the site of cumene hydroperoxide and vehicle injections show that VP-16 induced extensive hair follicle damage and dispersion of melanin in the skin of rats pre-treated with vehicle only ( Figure 1C )

Critically, AOD-9604 did not produce the metabolic side effects associated with full-length growth hormone, including no insulin resistance or glucose intolerance, no elevation of IGF-1 levels, no fluid retention or joint pain, and no cardiovascular parameter changes