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doi: 10.1007/s10072-014-2052-6 239 ZuinM.CervellatiC.BromboG.TrentiniA.RonconL.ZulianiG

Some of these typical acetazolamide related sideeffects (nausea, vomiting, confusion and drowsiness) cannot be clearly separated from the symptoms of AMS and might obscured the symptoms of AMS in acetazolamide administered individuals 51

This finding indicates the potential importance of ghrelin in the early stages of tumorigenesis ( Furthermore, the initial identification of ghrelin expression in esophageal squamous cell carcinoma was achieved through immunohistochemistry, wherein tissue ghrelin levels exhibited significant associations with the extent of differentiation, level of tumor invasion, lymph-vascular invasion, and tumor stage ( 8 Conclusion and prospects In conclusion, this review provides a comprehensive overview of the association between ghrelin and GI disorders

STZ is an antibiotic generated by Streptomyces achromogenes that selectively damages the pancreatic cells (O'Brien, Sakowski, & Feldman, 2014), leading to hypoinsulinemia and hyperglycemia (Ozaki, Terayama, & Matsuura, 2018)