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These findings demonstrate that GPX2 participates in maintaining the stemness of TKI-resistant cells by activating the Sonic Hedgehog signaling pathway

Effector T cells require fatty acid metabolism during murine graft-versus-host disease

doi: 10.1212/01.wnl.0000437297.05570.a2 63 Gaoni Y and MechoulamR

His favorite Cornell memory is riding the campus bus and listening to all the different languages that were mixed together. Wishing you well, Philip

Moreover, by using pharmacological and genetic approaches in human macrophages, REV-ERB has been shown to act as a pivotal intermediary between the molecular clock and inflammatory pathways, by regulating the expression of genes involved in human innate immunity, such as IL-6 56 , and repressing CCL2 gene expression directly through a RORE in the CCL2 promoter region 57 (Fig