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There are many mechanisms of skin aging, and researchers have proposed different models to explain the molecular basis of skin aging, including the theory of cellular senescence, the decline in cellular DNA repair and telomere loss, extranuclear mitochondrial DNA point mutations, oxidative stress, increased frequency of chromosomal anomalies, single-gene mutations, chronic inflammation, and others [13]

Preclinical research showed acetyl-L-carnitine prevented and mitigated nerve pain caused by the chemotherapy drug paclitaxel (Abraxane)

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