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Thus, both CYP2D6 and CYP3A4 are the main enzymes for the metabolism of risperidone to 9-hydroxyrisperidone

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Whereas proteasomal degradation of the NF-B inhibitory subunit IB-, nuclear translocation of NF-B and downstream activation of the pro-inflammatory environment was inhibited when bone marrow or peritoneal neutrophils are exposed to hydrogen peroxide [108]