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BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death

Additionally, we previously discovered that the transcriptional mediator complex contributes to antioxidant gene expression via a direct interaction between Nrf2 and a mediator subunit, MED16 (Figure 2) [31]

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For low glucose experiments cells were plated in Neurobasal-A Medium, no D-glucose, no sodium pyruvate, supplemented with 0,5 mg/ml D-Glucose, 1 mM sodium pyruvate (ThermoFisher), and the components previously described for complete NB media, and incubated at 37 and 5% CO 2 for 72 h

5mL per 100kg bodyweight