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Furthermore, an adenoviral vector harboring a synthetic gene for thymulin, stereotaxically injected in the rat brain, achieved a much longer expression than the adenovirally mediated expression in the brain of other genes, thus suggesting that an antiinflammatory activity of thymulin prevents the immune system from destroying virustransduced brain cells

86, 87 Similarly, IL-6 modulation of the claudin-2 gene induces intestinal epithelial TJ permeability through the JNK pathway

Most doctors are glad to add this when you mention the concern

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