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A few commenters expressed concern that this approach could distort results, limit the value of the ratings for patients, and fail to drive meaningful performance improvement, particularly given that many hospitals already receive two- or three-star ratings that signal a need for improvement in multiple respects

High-dose or poorly formulated over-the-counter products are more likely to cause issues than a medical-grade drip or injection from a reputable clinic

To overcome these challenges, future studies should focus on developing advanced imaging techniques, such as MRI, to track the real time biodistribution of MNPs (Remmo et al., 2024)

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