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Recent papers in the field of neurodegenerative diseases have examined the posttranscriptional regulation of proteins by microRNA (miRNA) [68,122], and one of the miRNAs, named miR-96-5p, was particularly upregulated in the brains of MSA patients [123]

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Collectively, we conclude that Q92 acts as an essential residue for high reactivity of GPx7 with H 2 O 2 and hence effective PDI oxidation of the enzyme