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140 Correspondingly, H3K9 exhibits remarkable hyperlactylation in VEGF-induced ECs and oxygen-induced retinopathy mouse retinas, leading to increased expression of angiogenic genes, including NECTIN1, TGFBR2, ABL1, PTGFR, LAMA4, CLASP2, PRCP, and EGFR

Ozone exposure impacts the central nervous system, leading to neurological illnesses including Alzheimers and Parkinsons diseases, cognitive deficits, and neuroinflammation (573)

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This is the hallmark of a homeostatic modulator rather than a direct agonist or antagonist