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Strong correlations were observed for intestinal and kidney models ( r = 0.99), with slightly lower correlation in liver models (r = 0.96), indicating minimal divergence and supporting their use for downstream PK/PD studies (Supplementary Fig

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Additionally, the heat stress marker hsp-16.2 was consistently downregulated with the glucose-fed bacterial diet as determined by both GFP fluorescence and mRNA expression (Supplementary Figures S3a and S3b)

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