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Anyone interested in the regulatory outcome should monitor the FDA's formal rulemaking process, which must follow the advisory committee recommendation before any change takes legal effect

The combined treatment reduced HbA1c to a greater degree considering it decreased by 2.2% with the combination of semaglutide and cagrilinide, 1.8% with semaglutide alone, and 0.9% with cagrilintide [2]

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Figure 1: Changes in body weight from baseline to the end of treatment at week 26 associated with the trial product estimand, in the randomly assigned treatment groups administered either 0.3 mg of cagrilintide, 0.6 mg of cagrilintide, 1.2 mg of cagrilintide, 2.5 mg of cagrilintide, 4.5 mg of cagrilintide, 3.0 mg of liraglutide, or a placebo