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Nurerk, P., Junden, S

(55) found that in a mouse model of corneal alkali injury, the expression of ROS was upregulated, oxidative stress increased, the expression of the gene Ptgs2, a key marker of ferroptosis, was elevated, the level of the lipid peroxidation product 4-hydroxynonenal (4-HNE) increased, and the level of the ferroptosis regulator GPX4 decreased, with mitochondrial damage

With RI at 10 mg the induction was in GST activity

As a result, there is a need to design more selective medicines with fewer adverse effects for non-target cells

Cell Host Microbe 17(5):565576 Gur TL, Worly BL, Bailey MT (2015) Stress and the commensal microbiota: importance in parturition and infant neurodevelopment