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Common reconstitution volumes: 20mg vial + 2mL BAC water = 10mg/mL concentration 40mg vial + 2mL BAC water = 20mg/mL concentration 40mg vial + 3mL BAC water = 13mg/mL concentration Add diluent slowly: Insert the needle into the vial at an angle and allow the water to flow down the inside wall of the vial

If youre already taking a B-complex or multivitamin that includes methyl donors, adding TMG might not be necessary

(PMID: 24724766)

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However, oral treatment with AMX0035 and TUDCA failed to meet primary clinical and electrodiagnostic endpoints in clinical trials