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MD simulations were carried out with the pmemded module of the AMBER 18 package in combination with the ff14SB force field 50

reported that mild Mthfr deficiency in aged Mthfr +/ mice and severe deficiency in young Mthfr / mice cause region-specific reductions in PP2A and LCMT1, particularly in the hippocampus and cerebellum [122]

Table 2.1 Essential and non-essential amino acids Non-protein amino acids There are also amino acids found in cells that are not incorporated into proteins