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Currently, no miRNA-targeted therapeutic has been approved for respiratory indications

The study in Ldlr / mice found that Atg16l1-deficient CD11b + DCs produced a TGF--dependent tolerance phenotype and promoted CD4 + Treg cell expansion, reducing the development of atherosclerosis

Using Mrx1-roGFP2, flow sorting, and RNA sequencing (RNA-Seq), we uncovered transcriptional differences among infected macrophages that create metabolically distinct niches, shaping Mtb subpopulations with varied redox potential and drug responses

Sandireddy et al reviewed that MASLD is not just a liver disease, but also has consequences on multiple other organ systems, including cardiac and renal, which can lead to both morbidity and mortality 27