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It is a cluster of overlapping biological dysfunctions that conventional medicines organ-by-organ approach is poorly equipped to address simultaneously

In our experimental conditions, Spirulina was also shown to modulate the systemic antioxidant defense system by lowering GPx-1 and upregulating GPx-3 and SOD-2, which is quite intriguing

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Moreover, ectopic expression of HFD-TAF12L partially rescued the TAF12 depletion phenotype, mimicking full-length full length TAF12L (Figure 3A