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7 Therapeutic approaches to mitigate BBB dysfunction and cognitive decline Intestinal ischemiareperfusion (I/R) injury and the resulting systemic inflammation can severely compromise the bloodbrain barrier (BBB), leading to cognitive dysfunction (Zhang et al., 2024b)

[DOI] [PubMed] [PMC] Copple BL, Bai S, Burgoon LD, Moon JO

Biochem J 176:351358 Google Scholar Lichtenthaler, HK (1999) The 1-deoxy-d-xylulose-5-phosphate pathway of isoprenoid biosynthesis in plants

Why This Is Confusing: A Crucial Distinction You might be wondering: If this is so rare, why have I heard so much about it, especially in relation to autism