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Consistent with Leydig cells from elderly men, immunofluorescent staining showed FOXO4 predominantly localized in the nucleus of these H 2 O 2 -induced senescent TM3 Leydig cells, but in the cytoplasm of untreated controls (Figure 3B)

They cannot bind to receptors properly, cannot be absorbed efficiently, and in some cases can provoke unwanted immune responses

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Conduct Thorough Patient Assessments Medical History : Check for pre-existing conditions (e.g., kidney issues, hormonal imbalances, or allergies)