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Exacerbation: An increase in severity of a condition usually used to imply a worsening of the state of the chest in CF

some of these cells create brainbody barriers (perineurial and subperineurial surface glial cells), others cover neuronal somata (cortex glia) and some ensheath synapses in neuropil (astroglia-like cells) 32,33

In proliferating cells, both ribose and NADPH are consumed in parallel to support proliferation, with the PPP mode determined by whether cellular demand for nucleotides or lipids is greater

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These changes decrease blood flow, increase the risk of thrombosis, and can ultimately lead to various cardiovascular events such as myocardial infarction, stroke, and peripheral arterial disease (Dasagrandhi et al., 2022)