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doi: 10.1038/s41443-022-00539-7 21 FischerSEhlertUAmielCR

Yes, but always do a patch test first

PMID 7559527

doi:10.1016/S0893-133X(97)00181-4

Multicollinearity issues/too many overlapping covariates : In this work, we start with a large number of covariates (300+) and many covariates overlap i.e