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Importantly, this table adds to the number of factors that were listed by Blundell et al

SDH: Succinate dehydrogenase TFAM: Mitochondrial transcription factor A TNF: Tumor necrosis factor-alpha References Bates GP, Dorsey R, Gusella JF, Hayden MR, Kay C, Leavitt BR, Nance M, Ross CA, Scahill RI, Wetzel R (2015) Huntington disease

Clinical data show moderate improvement in pigment index, not dramatic shade changes

Oxidative stress is defined as the deterioration of the oxidative balance due to the increase in reactive oxygen species such as hydroxyl radical, superoxide radical and hydrogen peroxide formed during cellular metabolism and the inadequacy of antioxidants that detoxify them ( Malondialdehyde (MDA) is a degradation product of large chain reactions that lead to the oxidation of polyunsaturated fatty acids

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