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Bevacizumab treatment for radiation brain necrosis: mechanism, efficacy and issues

Overall, this study positions ferroptosis as a temporally dynamic and context-dependent process within the complex landscape of ATN, rather than a static, cell-autonomous death program

Repeated freeze-thaw cycles should be strictly limited to no more than three, as each cycle promotes peptide bond hydrolysis and aggregation that progressively reduces recoverable bioactive peptide content

Following these guidelines is crucial, as using an incompatible diluent could cause precipitation of the drug or inactivation of the drugs therapeutic effect

Batebi, N