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doi: 10.1016/j.cmet.2016.06.004 61 KellyBONeillLA

Velnar T, Bailey T, Smrkolj V

Elevated levels of lactate in the TME hinder the export of lactate from human CTLs, consequently impeding the proliferation and cytotoxic effects of CTLs

After the removal of senescent cells, the percentage of Ki67 + cells, a marker of cell proliferation, was significantly reduced, especially in the basal layer of the epidermis (Fig