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The enzyme jasmonoyl isoleucine conjugate synthase 1 (JAR1) in the cytosol catalyses the final step, although at least one alternative enzyme to JAR1, designated GH3.10, is present in leaf tissue (but 12hydroxy-jasmonic acid is its preferred substrate)

(2012) demonstrated that long-term exposure to CP impaired autophagy leading to CP resistance, and interestingly, upregulation of autophagic response under such condition re-sensitized resistant cells to CP-induced cell death

Firas Jafri, Gyuhee Seong, and Tim Jang are equal first authors

GPX2 silencing relieves epithelial-mesenchymal transition, invasion, and metastasis in pancreatic cancer by downregulating Wnt pathway

Al-Ansari S, Zecha JAEM, Barasch A, de Lange J, Rozema FR, Raber-Durlacher JE