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Severe cases of dehydration will need urgent fluid replenishment through IV therapy, but it has proven to be beneficial for many patients who regularly experience mild to moderate dehydration

(54) successfully established an in vitro model using MH7A cells

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However, for the preparation of missions beyond Low Earth Orbit (LEO) and extended missions, such as the Moon and Mars missions, continued research using ground-based simulated platforms is necessary to develop efficient strategies and countermeasures that ensure the well-being and productivity of astronauts in space