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Most patients experience no adverse effects, and when present, theyre typically mild and transient including temporary digestive changes as the gut adjusts, minor nausea (usually resolving within days), or altered bowel patterns during initial therapy

J Clin Oncol 33(JCO/2014/565218):156-64, 2015

Investigation of the hypothalamopituitary-adrenal axis by low-dose (1 g) adrenocorticotrophic hormone test and metyrapone test in patients with chronic fatigue syndrome

There have been some studies linking the supplements with more muscle and less fat in people with normal levels of GH, but nothing definitive

Genetic predispositions may lead to disorders like polycystic ovary syndrome (PCOS) and endometriosis which produce hormonal imbalances that result in irregular periods