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Available from: [DOI] [PMC free article] [PubMed] [Google Scholar] 327.Noseworthy MD, Bray TM

[DOI] [PubMed] [Google Scholar] 24.Pico J., Khomenko I., Capozzi V., Navarini L., Biasioli F

It was found that the reactive dienes trans -cyclooctene 101 and norbornene 102 react relatively rapidly with suitable tetrazine dienophiles (which release nitrogen irreversibly on subsequent retro-[4+2]-cycloaddition) allowing protein labelling at rates up to 1,000 times faster than SPAAC in the case of trans -cyclooctene (Fig

Genet 43 , 115122 (1998)

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