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Suhail et al., 2020

doi: 10.1126/sciimmunol.abm5505 214 PandayA.SahooM

(Vadal et al., 2012) injected MSCs into IVDs in a rabbit model of degeneration and observed large osteophytes at the injection sites, suggesting that MSCs may unexpectedly cause bone hyperplasia

The rare autosomal recessive disorder Immerslund-Grasbeck (IGS) disease is caused by mutations in either the gene Amnion Associated Transmembrane Protein (AMN) or Cubilin (CUBN) gene responsible for the synthesis of cubam receptors (Sobczynska-Malefora et al., 2021)