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A.PiresJ

Immunol., 157, 1736-1 743 15

Inhibition of mTOR extends lifespan and restores or delays many features of aging (Cassano and Magini 2019)

When the NAD + metabolome is replete and undisturbed, as in young healthy animals that have not received chemotherapy, exogenous NAD + precursors are likely to be excreted as excess surplus, rather than accumulated