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coli uses a broad range of regulatory proteins to impart sophisticated control to survive exposure 41,42

R GSTP1 (pi class) has a common variant, Ile105Val (rs1695), that reduces catalytic efficiency for polycyclic aromatic hydrocarbons but increases activity toward certain drug substrates

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Acknowledgements We thank the Keizo Asami Institute (iLIKA) and Graduate Program in Biology Applied to Health (PPGBAS) for providing research infrastructure

RH, ROH, ROOH, and a relatively unreactive phenoxyl radical are formed when antioxidants (AH) react with R, RO, and ROO (RH)