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Antioxid Redox Signal 28(13):12241237

PLoS ONE 15 , e0241989 (2020)

For example, Felix Sommer et al

Third, clinical translation should include establishing multicenter ALS biobanks to validate associations between biomarkers such as ACSL4 and GPX4 and clinical measures including ALSFRS-R scores and survival, and conducting combined trials of ferroptosis inhibitors with mitochondrial protectants to evaluate therapeutic benefit in sporadic ALS