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doi: 10.1016/j.pep.2009.03.009

[DOI] [PMC free article] [PubMed] [Google Scholar] 229.Snchez-Dans A et al

Thus, oxaloacetate from glucose contributes to NEAA pools by yielding aspartate and asparagine, connecting carbohydrate metabolism to nucleotide synthesis and adaptive stress responses

Extending the treatment to 48 h led to IC 50 values of 8.70 M for ZOT 5 -1-Me and 12.00 M for ZOT 5 -1-Et, reflecting a marginal increase in cytotoxicity compared to the 24-h exposure