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In a clinical setting, where we are trying to repair a compromised reversal barrier , precision matters

Recondo G, Bahcall M, Spurr LF, Che J, Ricciuti B, Leonardi GC, Lo Y-C, Li YY, Lamberti G, Nguyen T, et al

Treatments in mice with imipramine, an antidepressant compound, were correlated with increased levels of FOXO1 and FOXO3 phosphorylation and consequent inactivation