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The application should be so light that it just barely covers the area without leaving it excessively wet or damp

doi: 10.1371/journal.ppat.1004160 289 SjlinderH.JonssonA.-B

Blood-brain barrier (BBB) is responsible for filtering the blood of toxic compounds to the brain and some drugs

The nuclear factor E2 related to factor 2-antioxidant/heme oxygenase 1 response element (Nrf2-ARE/HO-1), a key metabolic pathway for genetic signaling transduction of enzymes related to the antioxidant system, is impaired in vitiligo patients ( 2 O 2 )