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Bacterial species most often observed to be over-represented in CRC from these studies include Fusobacterium nucleatum (Fn), Enterococcus faecalis, Streptococcus gallolyticus ( SGG) , enterotoxigenic toxin producing Bacteroides fragilis (ETBF) , and Porphyromonas species ( Roseburia, Ruminococcus, Clostridium, Faecalibacterium and Bifidobacterium are generally depleted in CRC patients ( ks (polyketide synthase)+ Escherichia coli (pks+Ec), ETBF , Fn , and SGG , damage the gut-barrier lining and colonocyte DNA, increase proinflammatory cytokines and oxidative factors, and produce potentially carcinogenic toxins (61)

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It binds to copper, influencing gene expression to activate vital functions that improve skin texture, support hair follicle health, aid in healing, and reduce inflammation